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December 8, 2017
Zebrafish are rapidly becoming the ‘go-to’ animals in cancer research. Small and translucent, they breed rapidly and take up little room. And they grow transplanted cancer tumors in their little bodies very quickly. This gives doctors a clear view of why some cancers metastasize and recur. Eventually, this research will yield treatment for these recurrent […]
December 1, 2017
Priscila Daniele Ramos Cirilo, Luciana Nogueira de Sousa Andrade, Bruna Renata Silva Corrêa, Mei Qiao, Tatiane Katsue Furuya, Roger Chammas, Luiz Otavio Ferraz Penalva Background Melanoma is the most lethal type of skin cancer. Since chemoresistance is a significant barrier, identification of regulators affecting chemosensitivity is necessary in order to create new forms of intervention. […]
November 29, 2017
Authors Penalva LOF Sanford JR Precise control of messenger RNA (mRNA) fate—its translation, stability, and localization—is required for accurate eukaryotic gene expression and is of fundamental importance to human health and disease. Initial efforts to determine how the cell controls these processes focused on “who done it?” We now understand that many of the clues […]
October 28, 2017
Abhik Bandyopadhyay 1, Edward Favours 1, Doris A Phelps 1, Vanessa Del Pozo 1, Samson Ghilu 1, Dias Kurmashev 1, Joel Michalek 2, Aron Trevino 2, Denis Guttridge 3, Cheryl London 4, Kenji Hirotani 5, Ling Zhang 5, Raushan T Kurmasheva 1, Peter J Houghton 1 Abstract Background: Integrating molecularly targeted agents with cytotoxic drugs used in the curative treatment of pediatric cancers is complex. An evaluation was undertaken with the ERBB3/Her3-specific antibody patritumab (P) either alone or with the ERBB1/epidermal growth factor […]
October 19, 2017
RESEARCH: The Lancet Oncology: Recommendations for cardiomyopathy surveillance for survivors of childhood cancer: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group. Experts in late effects screening from the United States and Europe completed a combined review of current guidelines that direct screening for heart problems in survivors of childhood cancer. Participants in […]
October 18, 2017
Genomic Vision (Paris:GV) (Euronext: FR0011799907 – GV), a company specialized in the development of diagnostic tests for the early detection of cancers and genetic diseases, today reports of its second R&D Day which took place on October 16 in Paris and was attended by clients, investors, analysts, and journalists. This second edition was aimed at […]
October 18, 2017
October 9, 2017
Kennedie Bailey celebrated her 11th birthday in May with a sleepover, but she can’t remember much about the details because, shortly after, she was shocked to learn that she had a rare cancer. Aggressive rhabdomyosarcoma develops from connective tissues in the body, including muscles, bones, joints, and fat. It’s not uncommon for it to recur after […]
October 5, 2017
Pediatric Blood and Cancer: Electrophysiological effects of anthracyclines in adult survivors of pediatric malignancy. Researchers at Johns Hopkins Hospital conducted a retrospective chart review of 147 survivors of childhood cancer that were now over the age of 18. The goal of the study was to evaluate the correlation between abnormalities in electrocardiographic changes and cardiac […]
October 5, 2017
Researchers from the Greehey Children’s Cancer Research Institute at UT Health San Antonio co-authored a paper published Sept. 26 in Science Signaling that looks at the reliability of a common research tool to study RAS cancer mutations. RAS mutations are implicated in several cancers, including lung, colorectal, and pancreatic ductal carcinoma. The three RAS genes are the […]