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July 3, 2016
The Cancer Prevention & Research Institute of Texas has awarded nearly $11 million to the University of Texas Health Science Center at San Antonio in its latest funding round. That award includes $5 million to help establish the Texas Pediatric Patient-Derived Xenograft Facility. Peter Houghton, director of the Greehey Children’s Cancer Research Institute at the […]
July 1, 2016
Michael S Barker 1, Zheng Li 2, Thomas I Kidder 2, Chris R Reardon 2, Zhao Lai 3, Luiz O Oliveira 4, Moira Scascitelli 5, Loren H Rieseberg 6 Abstract Premise of the study: Like many other flowering plants, members of the Compositae (Asteraceae) have a polyploid ancestry. Previous analyses found evidence for an ancient duplication or possibly triplication in the early evolutionary history of the family. We sought to better […]
July 1, 2016
Subapriya Rajamanickam, Subbarayalu Panneerdoss, Aparna Gorthi, Santosh Timilsina, Benjamin Onyeagucha, Dmytro Kovalsky, Dmitri Ivanov, Martha A. Hanes, Ratna K. Vadlamudi, Yidong Chen, Alexander J. Bishop, Jack L. Arbiser and Manjeet K. Rao Abstract Purpose: The approaches aimed at inhibiting the ability of cancer cells to repair DNA strand breaks have emerged as promising targets for treating cancers. Here, we assessed the potential of imipramine blue (IB), a novel analog of antidepressant imipramine, to suppress breast cancer growth and metastasis by inhibiting […]
June 30, 2016
Yohei Niikura,Risa Kitagawa & Katsumi Kitagawa ABSTRACT CENP-A (Centromere protein A) is a histone H3 variant that epigenetically determines the centromere position, but the mechanism of its centromere inheritance is obscure. We propose that CENP-A ubiquitylation, which is inherited through dimerization between rounds of cell division, is a candidate for the epigenetic mark of centromere identity. […]
June 17, 2016
SAN ANTONIO – The doctors, staff and patients at the Greehey Children’s Cancer Research Institute are celebrating its latest grant, a $10.9 million donation from Cancer Prevention and Research Institute of Texas.
June 15, 2016
Surya P Rednam 1, Ayelet Erez 2, Harriet Druker 3, Katherine A Janeway 4, Junne Kamihara 4, Wendy K Kohlmann 5, Katherine L Nathanson 6, Lisa J States 7, Gail E Tomlinson 8, Anita Villani 3, Stephan D Voss 9, Joshua D Schiffman 5 10, Jonathan D Wasserman 11 Abstract Von Hippel-Lindau disease (vHL) is a hereditary tumor predisposition syndrome that places affected individuals at risk for multiple tumors, which are predominantly benign and generally occur in the central nervous system […]
June 11, 2016
Abstract Motivation: N 6 -methyl-adenosine (m 6 A) is the most prevalent mRNA methylation but the precise prediction of its mRNA location is important for understanding its function. A recent sequencing technology, known as Methylated RNA Immunoprecipitation Sequencing technology (MeRIP-seq), has been developed for transcriptome-wide profiling of m 6 A. We previously developed a peak calling algorithm called exomePeak. However, […]
June 3, 2016
The Cancer Prevention & Research Institute of Texas has awarded nearly $11 million to the University of Texas Health Science Center at San Antonio in its latest funding round. That award includes $5 million to help establish the Texas Pediatric Patient-Derived Xenograft Facility. Peter Houghton, director of the Greehey Children’s Cancer Research Institute at the […]
May 31, 2016
Hanane Ennajdaoui, Jonathan M Howard, Timothy Sterne-Weiler, Fereshteh Jahanbani, Doyle J Coyne, Philip J Uren, Marija Dargyte, Sol Katzman, Jolene M Draper, Andrew Wallace, Oscar Cazarez, Suzanne C Burns, Mei Qiao, Lindsay Hinck, Andrew D Smith, Masoud M Toloue, Benjamin J Blencowe, Luiz OF Penalva, Jeremy R Sanford Insulin-like growth factor 2 mRNA binding protein […]
May 20, 2016
The Greehey Children’s Cancer Research Institute at the Health Science Center garnered $10.9 million from the Cancer Prevention & Research Institute of Texas (CPRIT)―a larger amount than any other academic institution in the state. The Health Science Center received 24 percent of the $45.3 million awarded to 13 academic institutions on May 18. The grant was the […]