Cancer Cell: Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment

August 1, 2006

Author links open overlay panelAnuradha Budhu1, Marshonna Forgues1, Qing-HaiYe2, Hu-Liang Jia12, Ping He3, Krista A.Zanetti4, Udai S.Kammula5, Yidong Chen6, Lun-XiuQin2, Zhao-YouTang2, Xin WeiWang1 Summary Hepatocellular carcinoma (HCC) is an aggressive malignancy mainly due to metastases or postsurgical recurrence. We postulate that metastases are influenced by liver microenvironment. Here, we show that a unique inflammation/immune response-related signature is […]

Oncogene: Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells

November 13, 2005

M-H Tsai, X Chen, G V R Chandramouli, Y Chen, H Yan, S Zhao, P Keng, H L Liber, C N Coleman, J B Mitchell & E Y Chuang Abstract The p53 protein has been implicated in multiple cellular responses related to DNA damage. Alterations in any of these cellular responses could be related to increased genomic instability. Our previous study has shown that mutations in […]