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Scientific Reports: Differential network analysis reveals the genome-wide landscape of estrogen receptor modulation in hormonal cancers
November 12, 2016
Tzu-Hung Hsiao, Yu-Chiao Chiu, Pei-Yin Hsu, Tzu-Pin Lu, Liang-Chuan Lai, Mong-Hsun Tsai, Tim H.-M. Huang, Eric Y. Chuang Yidong Chen Abstract Several mutual information (MI)-based algorithms have been developed to identify dynamic gene-gene and function-function interactions governed by key modulators (genes, proteins, etc.). Due to intensive computation, however, these methods rely heavily on prior knowledge […]
Hyundai Hope on Wheels Awards $250,000 Research Grant to Ut Health Science Center San Antonio in Honor of National Childhood Cancer Awareness Month
September 12, 2016
San Antonio, TX – September 12 – Hyundai Hope On Wheels® (HHOW) and San Antonio-area Hyundai dealers will present UT Health Science Center San Antonio with a $250,000 Scholar Grant to be used to improve care and increase treatment options for kids with cancer. UT Health Science Center San Antonio was one of 24 recipients across the […]
UT Health SA Newsroom: Health Science Center, UTSA gain $4.6 million for cancer research
August 25, 2016
The Center for Innovative Drug Discovery (CIDD), a joint program of the UT Health Science Center San Antonio and The University of Texas at San Antonio (UTSA), is receiving a $4,598,728 grant from the Cancer Prevention & Research Institute of Texas (CPRIT). The grant, announced Aug. 17, will support CIDD research to design more-effective cancer drugs through […]
BMC Genomics: Detection of high variability in gene expression from single-cell RNA-seq profiling
August 22, 2016
Hung-I Harry Chen, Yufang Jin, Yufei Huang & Yidong Chen Abstract Background The advancement of the next-generation sequencing technology enables mapping gene expression at the single-cell level, capable of tracking cell heterogeneity and determination of cell subpopulations using single-cell RNA sequencing (scRNA-seq). Unlike the objectives of conventional RNA-seq where differential expression analysis is the integral component, the most important […]
BMC Genomics: CrossLink: a novel method for cross-condition classification of cancer subtypes
August 22, 2016
Chifeng Ma, Konduru S. Sastry, Mario Flore, Salah Gehani, Issam Al-Bozom, Yusheng Feng, Erchin Serpedin, Lotfi Chouchane, Yidong Chen & Yufei Huang Abstract Background We considered the prediction of cancer classes (e.g. subtypes) using patient gene expression profiles that contain both systematic and condition-specific biases when compared with the training reference dataset. The conventional normalization-based approaches cannot guarantee that the gene signatures in the reference […]
SA Business Journal: Cancer money to boost local pediatric research
July 3, 2016
The Cancer Prevention & Research Institute of Texas has awarded nearly $11 million to the University of Texas Health Science Center at San Antonio in its latest funding round. That award includes $5 million to help establish the Texas Pediatric Patient-Derived Xenograft Facility. Peter Houghton, director of the Greehey Children’s Cancer Research Institute at the […]
American Journal of Botany: Most Compositae (Asteraceae) are descendants of a paleohexaploid and all share a paleotetraploid ancestor with the Calyceraceae
July 1, 2016
Michael S Barker 1, Zheng Li 2, Thomas I Kidder 2, Chris R Reardon 2, Zhao Lai 3, Luiz O Oliveira 4, Moira Scascitelli 5, Loren H Rieseberg 6 Abstract Premise of the study: Like many other flowering plants, members of the Compositae (Asteraceae) have a polyploid ancestry. Previous analyses found evidence for an ancient duplication or possibly triplication in the early evolutionary history of the family. We sought to better […]
KSAT12: $10+ million grant helps survivor now working at cancer institute that saved him (Houghton, Chen, Ignatius, Shiio, mention)
June 17, 2016
SAN ANTONIO – The doctors, staff and patients at the Greehey Children’s Cancer Research Institute are celebrating its latest grant, a $10.9 million donation from Cancer Prevention and Research Institute of Texas.
SA Business Journal: Cancer money to boost local pediatric research
June 3, 2016
The Cancer Prevention & Research Institute of Texas has awarded nearly $11 million to the University of Texas Health Science Center at San Antonio in its latest funding round. That award includes $5 million to help establish the Texas Pediatric Patient-Derived Xenograft Facility. Peter Houghton, director of the Greehey Children’s Cancer Research Institute at the […]
UT Health SA Newsroom: CPRIT awards $10.9 million to Greehey institute for cancer research
May 20, 2016
The Greehey Children’s Cancer Research Institute at the Health Science Center garnered $10.9 million from the Cancer Prevention & Research Institute of Texas (CPRIT)―a larger amount than any other academic institution in the state. The Health Science Center received 24 percent of the $45.3 million awarded to 13 academic institutions on May 18. The grant was the […]