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May 25, 2021
Congratulations to Adam Kosti from the Luiz O.F. Penalva, PhD Lab on being awarded the Barbara Bowman Endowment In Cellular & Structural Biology Award for the second year in a row. Learn more about Adam’s related papers: Molecular Cancer Research: ELF4 Is a Target of […]
May 25, 2021
Shan Qi, a 3rd year PhD student in Dr. Yogesh Gupta’s laboratory at Greehey CCRI, received the prestigious Hibbs Award “for Research Excellence is a major award given annually to recognize exemplary achievement and research excellence to a student enrolled in Biomedical Mechanisms of Medicine (BMM).” The Hibbs prize was established by a generous endowment […]
May 21, 2021
The Robert Clark Frontiers of Translational Science Research Day showcases posters that illustrate completed or ongoing research projects in Translational Science. This year, due to current gathering restrictions, the event was hosted virtually. After a day full of innovative research presentations, Kathryn Crouch from the Greehey CCRI received an award for her presentation titled “Novel […]
May 18, 2021
Excerpt from "CSHL's COVID/SARS CoV2 Rapid Research Meeting Reports V" Structural biology, molecular biology, and immunology As with the previous two meetings, this one was broken up into sections by topic and the first up was “Host-virus Interactions/Structure.” There were some great talks looking at which animals are likely susceptible to the virus based on [...]May 13, 2021
Despite the breakthroughs being made in treating many cancers with less toxic, targeted, and immune-based therapies, Ewing sarcoma’s 40-year-old chemotherapy regimen remains a significant contributor to mortality and long-term cardiovascular complications adolescent and young adult cancer patients. An ongoing collaborative project initiated by the Rutledge Cancer Foundation collaborates with Qana Therapeutics, Greehey Children’s Cancer Research […]
May 13, 2021
Recently, Greehey CCRI principal investigator, Yogesh Gupta, PhD., was included as an invited speaker with prominent scientists from academia (Ian Wilson, Pamela Bjorkman, and others) and industry (Pfizer and Moderna) at a COVID-19 workshop organized by the Advanced Photon Source of Argonne National Laboratory, Chicago. Broadly, the workshop presented areas where structural biology research, including […]
April 13, 2021
Novel approach paves the way for a vast expansion in the number of drugs targeting osteosarcoma Abstract #LB008 HOUSTON — A preclinical study led by researchers at The University of Texas MD Anderson Cancer Center shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma tumor cells […]
March 10, 2021
Congratulations to Nighat Noureen, PhD, a postdoctoral fellow in the lab of Greehey CCRI principal investigator, Siyuan Zheng, PhD, on recently being awarded a CPRIT fellowship training grant. Dr. Noureen joined Dr. Zheng’s lab in June 2018. Her first project was to develop a computational method to quantify telomerase activity in cancer and […]
February 26, 2021
On February 25, 2021, Dr. Yogesh Gupta delivered an invited talk at the International Society for Stem Cell Research COVID network meeting chaired by Hans-Willem Snoeck. MD, PhD (Columbia Univ.) and Todd McDevitt, PhD (Gladstone Inst., UCSF). At this meeting, Dr. Gupta presented his recent research on nonstructural proteins (nsps) of SARS-CoV-2. Some […]
January 8, 2021
Emily Selig recently earned her PhD at the University of Melbourne, Australia where she was employing biophysical and biochemical approaches to investigate the mechanisms by which the small heat-shock proteins aB-crystallin and heat-shock protein 27 (Hsp27) inhibit protein misfolding and incorporation into amyloid fibrils. These proteins are ubiquitously expressed chaperone proteins responsible […]