All News

BioPhysics Journal: Unraveling the phase separation of EWS low complexity domain using molecular dynamics simulations (Libich Lab)

March 3, 2023

Kandarp A. Sojitra 1, Courtney Johnson 2 3, Erich Sohn 2 3, David Libich 2 3, Jeetain Mittal 1 EWS, an RNA-binding protein, is responsible for gene expression, cell signaling, RNA processing, and transport. It is a member of the FET (FUS, EWS, TAF15) family, whose derailed phase separation is known to cause many neurodegenerative [...]

Cancers Journal (MDPI) Guest Editor, Raushan Kurmasheva, PhD, invites relevant research work for publication.

February 24, 2023

Raushan Kurmasheva (Guest Editor) invites relevant research work for publication in a new Special Issue of the Cancers Journal (MDPI) titled “Pediatric Cancer: From Molecular Targets to Effective Therapies.” Please, find more information here:https://www.mdpi.com/journal/cancers/special_issues/I1WGF17062 Feel free to contact Dr. Kurmasheva directly with any questions on this submission.

Nature Communications: DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation (Sung Lab)

February 7, 2023

Youngho Kwon, Heike Rösner, Weixing Zhao, Platon Selemenakis, Zhuoling He, Ajinkya S. Kawale, Jeffrey N. Katz, Cody M. Rogers, Francisco E. Neal, Aida Badamchi Shabestari, Valdemaras Petrosius, Akhilesh K. Singh, Marina Z. Joel, Lucy Lu, Stephen P. Holloway, Sandeep Burma, Bipasha Mukherjee, Robert Hromas, Alexander Mazin, Claudia Wiese, Claus S. Sørensen & Patrick Sung Abstract The [...]

International Journal of Molecular Sciences: Therapeutic Targeting of Ovarian Cancer Stem Cells Using Estrogen Receptor Beta Agonist (Lai)

July 12, 2022

Yi He 1,2, Salvador  Alejo 1, Prabhakar Pitta Venkata 1, Jessica D. Johnson 1, Ilanna Loeffel 1, Uday P. Pratap 1, Yi Zou 3, Zhao Lai 3, Rajeshwar R. Tekmal 1,4, Edward R. Kost 1 and Gangadhara R. Sareddy 1,4,* Abstract Ovarian cancer (OCa) is the deadliest gynecologic cancer. Emerging studies suggest ovarian cancer stem [...]


International Journal of Cancer: Integrin alpha 6 (ITGA6) is upregulated and drives hepatocellular carcinoma progression through integrin α6β4 complex (Lai, Chen)

June 6, 2022

Integrin alpha 6 (ITGA6) is upregulated and drives hepatocellular carcinoma progression through integrin α6β4 complex Guixi Zheng,Hakim Bouamar,Matyas Cserhati,Carla R. Zeballos,Isha Mehta,Habil Zare,Larry Broome,Ruolei Hu,Zhao Lai,Yidong Chen,Francis E. Sharkey,Meenakshi Rani,Glenn A. Halff,Francisco G. Cigarroa,Lu-Zhe Sun Abstract Integrin α6 (ITGA6) forms integrin receptors with either integrin β1 (ITGB1) or integrin β4 (ITGB4). How it functions to [...]

Nature Communications: Bloom helicase mediates formation of large single–stranded DNA loops during DNA end processing (Sung)

April 27, 2022

Chaoyou Xue, Sameer J. Salunkhe, Nozomi Tomimatsu, Ajinkya S. Kawale, Youngho Kwon, Sandeep Burma, Patrick Sung & Eric C. Greene Nature Communications volume 13, Article number: 2248 (2022) Cite this article Abstract Bloom syndrome (BS) is associated with a profoundly increased cancer risk and is caused by mutations in the Bloom helicase (BLM). BLM is involved in the nucleolytic processing of the [...]

Greehey CCRI to be at Southtown Siclovia, hosted by SATX YMCA

March 23, 2022

Happy Wednesday, everyone! Riding in the Gear Up Against Kids Cancer on April 2nd but your bike isn't flying as it should? Then come see us at Siclovia this Sunday 3/27 10a-2P, with our good friends from Ride In Paradise Bicycle Shop Look for our HUGE ORANGE canopy in front of The Good Kind Cafe [...]

Angelina Vaseva, PhD to Receive NCI Method to Extend Research in Time (MERIT)(R37) Award.

March 2, 2022

Angelina Vaseva, PhDAssistant Professor,Department of Molecular Medicine,Greehey Children’s Cancer Research Institute Congratulations to Dr. Vaseva on being awarded an NCI Method to Extend Research in Time (MERIT)(R37) Award. NCI R37 award provides longer-term grant support to Early Stage Investigators (ESIs) that receive outstanding R01 grant scores. Eligible investigators may obtain up to seven years of [...]

Patrick Sung, D. Phil, Appointed as Director of the Greehey Children’s Cancer Research Institute at UT Health San Antonio.

February 7, 2022

Patrick Sung, DPhil, director of the Greehey Children’s Cancer Research Institute We are pleased to announce the appointment of Patrick Sung, D. Phil, as director of the Greehey Children’s Cancer Research Institute (GCCRI) at UT Health San Antonio, effective March 1, 2022. Dr. Sung currently serves as professor and interim chair of the Department of [...]