All News
Investigative & Clinical Urology: Microbiome diversity in carriers of fluoroquinolone resistant Escherichia coli
March 1, 2019
Michael A Liss 1 2, Robin J Leach 1 3, Elizabeth Rourke 1, Allison Sherrill 1, Teresa Johnson-Pais 1 3, Zhao Lai 4, Joseph Basler 1, James R White 5, Jan E Patterson 6 Abstract Purpose: Fluoroquinolone-resistant (FQR) Escherichia coli causes transrectal prostate biopsy infections. In order to reduce the colonization of these bacteria in carriers, we would like to understand the surrounding microbiome to determine targets for decolonization. Materials and methods: We perform an observational study to […]
Genome Research: PepQuery enables fast, accurate, and convenient proteomic validation of novel genomic alterations
March 1, 2019
Bo Wen, Xiaojing Wang, Bing Zhang Massively parallel or second-generation sequencing-based genomic studies continuously identify new genomic alterations that may lead to novel protein sequences, which are attractive candidates for disease biomarkers and therapeutic targets after proteomic validation. Integrative proteogenomic methods have been developed to use mass spectrometry (MS)-based proteomics data for such validation. These […]
Bexar County Medical Society: Feb 2019 (Rao Lab)
February 28, 2019
AHA Research – Circulation Research: Abstract 112: Doxorubicin Alters Cardiac Fibroblast Phenotype
February 28, 2019
Trevi R Mancilla, and Gregory J Aune Abstract The oldest cohort of childhood cancer survivors is entering into their sixth decade. The milestone comes with the knowledge that this population is at 15 times greater risk of cardiovascular events than the general population. One factor in this is doxorubicin, a chemotherapeutic drug commonly used to treat […]
UT Health SA Newsroom: Greehey researcher receives UT System’s Rising STARs award
February 26, 2019
Siyuan Zheng, PhD, assistant professor in the Department of Epidemiology and Biostatistics in the Long School of Medicine, has received a Rising STARs Award from the UT System. The award for early-career investigators comes with a $250,000 grant.
PNAS: Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR
February 26, 2019
Samuel A. Kotler, Vitali Tugarinov, Thomas Schmidt, Alberto Ceccon, David S. Libich, Rodolfo Ghirlando, Charles D. Schwieters, and G. Marius Clore Abstract The N-terminal region of the huntingtin protein, encoded by exon-1, comprises an amphiphilic domain (httNT), a polyglutamine (Q n ) tract, and a proline-rich sequence. Polyglutamine expansion results in an aggregation-prone protein responsible for Huntington’s disease. Here, we study the earliest events […]
San Antonio Business Journal: SA gets small share of more than $90M in state cancer research money
February 22, 2019
The Cancer Prevention and Research Institute of Texas has awarded 54 new academic research, prevention and product development grants totaling nearly $96 million. San Antonio’s cut is $3 million. All three Alamo City grants will support research at UT Health San Antonio. They include a pair of $900,000 awards and one for $1.2 million. Dr. Yuzuru […]
UT Health Newsroom: UT Health San Antonio researchers awarded $3 million for cancer studies
February 22, 2019
Ewing sarcoma research Yuzuru Shiio, MD, PhD, of the Greehey Children’s Cancer Research Institute at UT Health San Antonio, was awarded $1.2 million to further studies of Ewing sarcoma, a pediatric bone and soft tissue cancer. The median age of Ewing sarcoma patients is 15 years, and more than half of patients are adolescents. Dr. […]
SA MD News: South Texas Pediatric Blood and Cancer Center: Serving South Texas’ Most Seriously Ill Children Through Cancer Care and Research
February 7, 2019
Expert pediatric cancer physicians and researchers at UT Health San Antonio are working to improve the lives of children with cancer, both for today and tomorrow. UT Health San Antonio, in partnership with the University Health System, offers advanced care for children battling cancer through the South Texas Pediatric Blood and Cancer Center. The team, […]
Pharmacy Times: Chemotherapies May Have Varying Long-Term Cardiovascular Risk
February 6, 2019
By studying the outcomes of more than 28,000 long-term childhood cancer survivors in the United States and Europe, researchers found that exposure to different anthracyclines results in variable long-term cardiovascular risk.