Scientific Reports: “Transcriptomic Sex Differences in Sensory Neuronal Populations of Mice”

September 23, 2020

Jennifer Mecklenburg 1, Yi Zou 2, Andi Wangzhou 3, Dawn Garcia 2, Zhao Lai 2 4, Alexei V Tumanov 5, Gregory Dussor 3, Theodore J Price 3, Armen N Akopian 6 7 Abstract Many chronic pain conditions show sex differences in their epidemiology. This could be attributed to the sex-dependent differential expression of genes (DEGs) involved in nociceptive pathways, including sensory neurons. This study aimed to identify sex-dependent DEGs in estrous female versus male […]

Advanced Photon Source: How SARS-CoV-2 RNA Evades Host Immune Responses (Gupta Lab)

August 26, 2020

As we all know too well, the virus SARS-CoV-2 causes severe respiratory illness COVID-19. In parallel with the critical search for a cure, scientists are working diligently to develop effective treatments that can help lower the morbidity of this deadly virus. To develop these therapeutics, we must understand how the virus is able to invade […]

Luiz O.F. Penalva PhD Awarded CPRIT Grant to Study New Glioblastoma (GBM) Regulator

August 20, 2020

PROJECT SUMMARY Glioblastoma (GBM) is the most common and most aggressive brain tumor type among adults with a 14 months average patient survival. Despite all genomic efforts in recent years, novel therapies based on GBM common mutations and alterations have been disappointing. To build an alternative route, we have been focusing on oncogenic RNA binding […]

Alexander Pertsemlidis, PhD Co-Awarded National Science Foundation Grant.

August 20, 2020

PI: Leonidas Bleris, PhD                       Co-PI: Alexander Pertsemlidis, PhD (UT Dallas)                                              (UT Health San Antonio) PROJECT SUMMARY Collaborative Research: Unraveling extracellular microRNA communication Overview: […]

Luiz O.F. Penalva PhD Awarded CPRIT Grant to Study Glioblastoma (GBM)

August 20, 2020

 PROJECT SUMMARY Glioblastoma (GBM) is the most common and most aggressive brain tumor type among adults with a 14 months average patient survival. Despite all genomic efforts in recent years, novel therapies based on GBM common mutations and alterations have been disappointing. To build an alternative route, we have been focusing on oncogenic RNA binding [...]

Cellular and Molecular Bioengineering: Scaffold Architecture and Matrix Strain Modulate Mesenchymal Cell and Microvascular Growth and Development in a Time Dependent Manner

August 18, 2020

2020 CMBE Young Innovators issue Gennifer Chiou, Elysa Jui, Allison C. Rhea, Aparna Gorthi, Solaleh Miar, Francisca M. Acosta, Cynthia Perez, Yasir Suhail, Kshitiz, Yidong Chen, Joo L. Ong, Rena Bizios, Christopher Rathbone & Teja Guda Abstract Background Volumetric tissue-engineered constructs are limited in development due to the dependence on well-formed vascular networks. Scaffold pore size […]

Laboratory Equipment: Coronavirus Makes Changes That Cause Cells Not to Recognize it

July 28, 2020

With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in. On July 24 in Nature Communications, researchers at The University of Texas Health Science Center at San Antonio (UT Health San […]

ABC Spain: They discoverd how the coronavirus camouflages itself to infect cells

July 27, 2020

The SARS-CoV-2 coronavirus is capable of camouflaging itself to trick cells into entering them without causing any alarm. This is the conclusion of a study carried out by researchers at the University of Texas Health Sciences Center at San Antonio (UT Health San Antonio), published in “Nature Communications.”