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August 20, 2020
PROJECT SUMMARY Glioblastoma (GBM) is the most common and most aggressive brain tumor type among adults with a 14 months average patient survival. Despite all genomic efforts in recent years, novel therapies based on GBM common mutations and alterations have been disappointing. To build an alternative route, we have been focusing on oncogenic RNA binding [...]August 18, 2020
2020 CMBE Young Innovators issue Gennifer Chiou, Elysa Jui, Allison C. Rhea, Aparna Gorthi, Solaleh Miar, Francisca M. Acosta, Cynthia Perez, Yasir Suhail, Kshitiz, Yidong Chen, Joo L. Ong, Rena Bizios, Christopher Rathbone & Teja Guda Abstract Background Volumetric tissue-engineered constructs are limited in development due to the dependence on well-formed vascular networks. Scaffold pore size […]
August 6, 2020
Adam Kosti 1 2, Patricia Rosa de Araujo 1 2, Wei-Qing Li 1 3, Gabriela D A Guardia 4, Jennifer Chiou 5, Caihong Yi 1, Debashish Ray 6, Fabiana Meliso 4, Yi-Ming Li 3, Talia Delambre 1, Mei Qiao 1, Suzanne S Burns 1, Franziska K Lorbeer 1, Fanny Georgi 1, Markus Flosbach 1, Sarah Klinnert 1, Anne Jenseit 1, Xiufen Lei 1, Carolina Romero Sandoval 1, Kevin Ha 6, Hong Zheng 6, Renu Pandey 1, Aleksandra Gruslova 7, Yogesh K Gupta 1, Andrew Brenner 8, Erzsebet Kokovay 2, Timothy R Hughes 6 9 10, Quaid D Morris 6 9 11, Pedro A F Galante 12, Stefano Tiziani 13, Luiz O F Penalva 14 15 Abstract Background: RNA-binding proteins (RBPs) function as master regulators […]
August 3, 2020
Rebecca K Lane 1, Hongyan Guo 2, Amanda D Fisher 1, Jonathan Diep 3, Zhao Lai 4 5, Yidong Chen 5 6, Jason W Upton 7, Jan Carette 3, Edward S Mocarski 8, William J Kaiser 9 Abstract Herpesviruses are ubiquitous human pathogens that cause a wide range of health complications. Currently, there is an incomplete understanding of cellular factors that contribute to herpesvirus infection. Here, we report an antiviral necroptosis-based genetic screen to identify novel […]
July 30, 2020
Researchers announced Friday that they have discovered an enzyme that helps COVID-19 enter cells in the human body, allowing the infection to grow. Called non-structural protein 16, or nsp16, the enzyme is produced by the new coronavirus and acts as a “camouflage,” tricking human cells into thinking that the virus is “part of its own code and […]
July 28, 2020
SOURCE: WOAI Broadcast Date: July 27, 2020 A new discovery by researchers right here in San Antonio is giving doctors a better idea about how the coronavirus works. “I’m still not 100 percent,” said Rudy Palacios, a man who battled COVID-19 in a hospital for 16 days. “I actually was released from the hospital on […]
July 28, 2020
With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in. On July 24 in Nature Communications, researchers at The University of Texas Health Science Center at San Antonio (UT Health San […]
July 27, 2020
The SARS-CoV-2 coronavirus is capable of camouflaging itself to trick cells into entering them without causing any alarm. This is the conclusion of a study carried out by researchers at the University of Texas Health Sciences Center at San Antonio (UT Health San Antonio), published in “Nature Communications.”
July 26, 2020
Scientists, including those of Indian-origin, have resolved the structure of a molecule which the novel coronavirus uses to make its genetic sequence seem like a part of the host’s own, an advance that may lead to the development of new antiviral drugs against Covid-19. According to the study, published in the journal Nature Communications, the […]